Dental Stem Cells

Prepare today for your health capital of tomorrow!

The conservation of dental stem cells is now accessible to all and can be essential in the treatment of diseases by future cell therapies. Stem cells of dental origin, pluripotent mesenchymal, are capable of producing all cell types.

A pioneer in the field, Rhône Dental Clinic offers an innovative protocol, in partnership with a bio bank. Take advantage of the extraction of a tooth or your wisdom teeth to harvest, cultivate and sustainably preserve your dental stem cells.

These cells have an origin very close to all the cells that will give the neurons, the brain, the nerves, the spinal cord ...

Stem cells are the mother cells of all organs and tissues of the human body.
A stem cell is an undifferentiated cell that is characterized by two essential properties: its capacity to generate specialized cells by cell differentiation and an ability to maintain itself by proliferation in the body (self-renewal), or indefinitely, in culture.

Stem cells play a very important role in the development of organisms as well as in maintaining their integrity throughout life.

Why is it so important to store and grow a stock of your stem cells in the laboratory? ?

Adult stem cells are rare since once growth is complete, the need to proliferate can become dangerous. Stem cells, therefore, persist in restricted areas within each tissue. These “niches” have complex and regulated maintenance mechanisms to produce only the cells necessary to maintain a functional organism.
In medicine, stem cells have been the subject of extensive research since the ’90s.

In fact, cellular therapy nurtures the hope of regenerating or repairing damaged cells or tissues or even creating all of them, and ideally reconstructing.organs.

Adult stem cells, found in dental pulp, umbilical cord, bone marrow and adipose tissue, are already used in some therapies and clinical trials.
Stem cells of the bone marrow are today the most studied and most used. However, the dental stem cells have a much higher and faster reproductive capacity than bone marrow stem cells.
The advantage is to obtain stem cells that can be easily isolated, frozen, and multiplied in large quantities by cell cultures in vitro, before being used.
Dental stem cells and therapeutic applications
Dental stem cells and therapeutic applications Remnants of embryonic development, stem cells of dental origin are mesenchymal pluripotent, meaning that they are capable of producing cells of very different morphology and functions.

The most recent scientific studies have identified the therapeutic regeneration capabilities of dental stem cells in the following cases

Reconstruction of the tooth support tissue
Reconstruction of the cornea of the eye
Autoimmune diseases
Liver cells
Cartilage production

Production of cardiac cells
Neurone production
Revascularization of cardiac tissues
Improved vascularization of a tissue
Muscular dystrophy

Do you wish to benefit from a stem cell collection?

Rhône Dental Clinic adapts to the most demanding schedules and to the private requirements of each patient. We guarantee you a strict punctuality and offer an emergency service if necessary.

What teeth can we take?

Milk teeth are a source of stem cells in patientsaged 5 to 12 years.
Onlythe incisors and caninesare removed.They must be slightly mobile and free of cavities or reconstructions..
Wisdom teeth have a larger pulp chamber in whichtem cells will be more viable. The extracted tooth must be intact, without decay or discoloration.

How the protocol is implemented?

After extraction of the tooth, a secure package is sent to the laboratory with the serology of the patient. The lab opens the tooth to extract the dental pulp which is dissociated to obtain a tissue and a cell suspensionlaboratory with the serology of the patient. The lab opens the tooth to extract the dental pulp which is dissociated in order to obtain a tissue and a cell suspension.

Once sterile, viable cells will be counted and identified by number, and their RNA extracted to identify CD34 + biomakers confirming the presence of mesenchymal stem cells.

A small amount of stem cells is enough to produce millions of others, and multiply enough to reach the number needed for treatment.confirming the presence of mesenchymal stem cells.

This cell culture process is called cell expansion and means that only one cell can multiply, under carefully controlled laboratory conditions, and it may be used later for multiple applications or as a transplant.